The BRCA Founder Outreach (BFOR) Study is a new research initiative. It will pioneer new ways to integrate genetic testing into medical care. This model combines the convenience of direct-to-consumer genetic tests along with the advantages of receiving testing with the guidance of a medical care provider.
BFOR seeks to increase access to testing for one of the most common tests for hereditary cancer, BRCA genetic mutations. These mutations of BRCA genes are associated with greater risks for several types of cancer, including breast, ovarian, and prostate cancer.
BFOR will provide patients, families, and their doctors with better information to make important decisions about their health care. This information will help thousands of people to reduce their cancer risks.
The study will offer women and men of Ashkenazi Jewish (Eastern European) ancestry, age 25 or older, genetic testing for common BRCA mutations. This group is at least ten times more likely than the general population to inherit certain kinds of BRCA mutations.
BFOR will explore how our health care system can use genetic testing in new ways to improve and personalize medical care in the future.
BFOR offers targeted BRCA genetic testing for the most common mutations at no cost to participants. To learn more, please see our FAQ . The pilot phase of the BFOR study is now open in the New York, Boston, Philadelphia, and Los Angeles metropolitan areas. BFOR may expand to other areas in the United States in the future.
Have more questions? Learn more about the process of participating in the BFOR study, visit our frequently asked questions, or visit our BRCA information page.
Genetic testing provided by Quest Diagnostics.
BFOR in the News
BFOR is an independent research initiative, directed by leading experts in the fields of cancer research and genetics. BFOR team members have led efforts to identify genetic changes that cause cancer. They have also developed approaches to early detection, prevention, and treatment.
The study is made possible by the generosity of individual philanthropists.
BFOR Executive Committee
Kenneth Offit, MD, MPH: Memorial Sloan Kettering Cancer Center, New York City
Mark Robson, MD: Memorial Sloan Kettering Cancer Center, New York City
Beth Karlan, MD: Cedars-Sinai Medical Center, Los Angeles
Judy Garber, MD, MPH: Dana Farber Cancer Institute, Harvard Medical School, Boston
Susan Domchek, MD: Basser Center for BRCA, University of Pennsylvania, Philadelphia
Katherine L. Nathanson, MD: Abramson Cancer Center and Basser Center for BRCA, University of Pennsylvania, Philadelphia
Nadine Tung, MD: Beth Israel Deaconess Medical Center and Harvard Medical School, Boston
Jeremy N. Block, PhD, MPP: Executive Director, Ex Officio
BFOR Scientific Advisory Board
Stephen J. Chanock, MD, Director, National Cancer Institute, Division of Cancer Epidemiology & Genetics
Mary Freivogel, MS, CGC, President, National Society of Genetic Counselors
Ian Jacobs BA, MA, MBBS, MD, FRCOG, President and Vice-Chancellor, University of New South Wales
Susan L. Neuhausen, PhD
The Morris & Horowitz Families Professor in Cancer Etiology & Outcomes Research
Director, Division of Biomarkers of Early Detection and Prevention, Department of Population Sciences
Co-leader, Cancer Control and Population Sciences Program, Comprehensive Cancer Center City of Hope
Eileen E. Reynolds, MD
Chief, Division of General Medicine, Beth Israel Deaconess Medical Center
Vice Chair for Education, Department of Medicine, Beth Israel Deaconess Medical Center
Associate Professor of Medicine, Harvard Medical School
Immediate-Past President of the Society of General Internal Medicine
BFOR Community Advisory Board
Andrew Abramson: Co-Founder/Treasurer, Cure Breast Cancer Foundation
Elana Silber: Executive Director, Sharsheret
Douglas S. Rabin MD: Reproductive Endocrinologist, Ob/Gyn
Julie Somers and Barry Shrage: Combined Jewish Philanthropies
Tresa Grauer: Jewish Reconstructionist Communities - Reconstructionist Rabbinical College
Jay Sanderson and Julie Platt: The Jewish Federation of Greater Los Angeles
Valerie Lowenstein: Hadassah, The Women’s Zionist Organization of America, Inc.
Robin Ballin: JCC Association of North America
Sue Friedman, DVM: Executive Director,FORCE
Rabbi Lisa Gelber: Congregation Habonim New York, NY
BFOR Community Partnerships